Coronary artery disease
Coronary artery disease develops when the principal blood vessels in your heart become damaged or diseased. Inflammation and cholesterol-containing deposits (plaques) in your coronary arteries cause coronary artery disease.
The coronary arteries give blood, oxygen, and nourishment to your heart. The formation of plaque can narrow these arteries, limiting blood flow to the heart. Chest pain (angina), shortness of breath, and other signs and symptoms of coronary artery disease may develop as a result of reduced blood flow. A total blockage could trigger a heart attack.